基本情况

李灿鹏，男，白族，1974年12月生，日本国立鹿儿岛大学博士、云南大学教授。主要从事分析化学、材料化学和食品及生物安全检测方面的研究工作。目前为止，在 Nanoscale;  Oncotarget; Biosens. Bioelectron.;  ACS Appl. Mater. Inter.;  Anal. Chim. Acta.;  Analyst;  Sens. Actuator B-Chem.;  RSC Adv.;  J. Agric. Food Chem.;  Food Chem.;  LWT-Food Sci. & Technol. 等国际刊物上发表40多篇SCI论文, 其中第1或通讯作者35篇,1区论文17篇，IF>7的论文10篇，单篇最高IF=7.8，总影响因子超过140。同时，在国家级出版社出版了3部教材，其中主编2部，副主编1部。获得1项中国发明专利。现为云南省中青年学术与技术带头人、昆明市中青年学术带头人、云南大学第三批青年英才培育对象、云南大学青年骨干教师。

担任Scientific Reports;  Biosens. Bioelectro.;  Oncotarget;  Anal. Chim. Acta;  J. Hazard. Mater.;  Electrochim. Acta.;  IONICS;  ACS Sensors;  J. Mater. Chem. C;  Int. J. Environ. Anal. Chem.;   RSC Adv.;  J. Agric. Food Chem.;  Food Chem.;  Food Rev. Int.;  Food Res. Int.;  J. Food Sci. & Technol.;  Molecu. Nutri. Food Res.;  Biotechnol. Progr.等SCI刊物的审稿人。

受教育情况及工作经历

1. 受教育情况：

1995.09-1999.07:  云南农业大学食品科学部  本科

2000.04-2005.03:  日本国立鹿儿岛大学农学研究科  硕士，博士

2. 工作经历：

1999.09-1999.12:  云南农业大学食品科学部  助教

2005.04-2006.03:  日本国立鹿儿岛大学农学部 研究助手

2006.04-2006.09:  日本京都PharmaFoods International Co., Ltd公司  研究组长2006.10-至今   :  云南大学化学科学与工程学院 教授

研究领域和兴趣

[1] 基于超分子识别的光/电化学/生物传感器的研究及其应用

[2] 新型功能纳米材料在传感器中的应用研究

[3] 功能食品研发

[4] 食品及生物安全检测

工作业绩

1、科研论文(*通讯作者)

Zhao, H., Wang, S., Guo, L., Du, Y., Liu, L., Ma, T., Otecko, N.O., Li, C.-P.*, Zhang,  Y.* Fixed differences in the 3'UTR of buffalo PRNP gene provide binding sites for miRNAs post-transcriptional regulation. Oncotarget, DOI:10.18632/oncotarget. 17545 (SCI, IF=5.0)

Zhao, H., Liu, F., Wu, S., Yang, L.,* Zhang, Y.*, and Li, C. P.* Ultrasensitive electrochemical detection of Dicer1 3’UTR for the fast analysis of alternative cleavage and polyadenylation. Nanoscale, 2017, 9, 4272-4282. (SCI, IF=7.8)

Zhao, G., Yang, L., Wu, S., Zhao, H.,* Tang, E*, and Li, C. P.* The synthesis of amphiphilic pillar[5]arene functionalized reduced graphene oxide and its application as novel fluorescence sensing platform for the determination of acetaminophen. Biosens. Bioelectron., 2017, 91, 863-869. (SCI, IF=7.5)

Zhao, H., Yang, L., Li, Y., Ran, X., Ye, H., Zhao, G. Zhang, Y., Liu, F., and Li, C. P.*  A comparison study of macrocyclic hosts functionalized reduced graphene oxide for electrochemical recognition of tadalafil. Biosens. Bioelectron., 2017, 89, 361-369. (SCI, IF=7.5)

Yang, L., Zhao, H., Li, Y., Zhang, Y., Ye, H., Zhao, G. Ran, X., Liu, F., Li, C. P.* Insights into the recognition of dimethomorph by disulfide bridged β–cyclodextrin and its high selective fluorescence sensing based on indicator displacement assay. Biosens. Bioelectron., 2017, 87, 737-744. (SCI, IF=7.5)

Yang, L., Ran, X., Cai, L., Li, Y., and Zhao, H.,* and Li, C. P.* Calix[8]arene functionalized single-walled carbon nanohorns for dual-signalling electrochemical sensing of aconitine based on competitive host-guest recognition. Biosens. Bioelectron., 2016, 83, 347-352. (SCI, IF=7.5)

Yang, L., Xie, X., Cai, L., Ran, X., Li, Y., Yin, T., and Zhao, H.,* and Li, C. P.*  p-Sulfonated calix[8]arene functionalized graphene as a "turn on"fluorescent sensing platform for aconitine determination. Biosens. Bioelectron., 2016, 82, 146-154. (SCI, IF=7.5)

Yang, L., Zhao, H., Li, Y., Ran, X., Deng, G., Xie, X., and Li, C. P.* Fluorescent detection of tadalafil based on competitive host–guest interaction using p-sulfonated calix[6]arene functionalized graphene.  ACS Appl. Mater. Inter., 2015, 7, 26557-26565. (SCI, IF=7.1)

Yang, L., Fan, S., Deng, G., Li, Y., Ran, X., and Zhao, H.,* and Li, C. P.* Bridged β-cyclodextrin-functionalized MWCNT with higher supramolecular recognition capability: The simultaneous electrochemical determination of three phenols.  Biosens. Bioelectron., 2015, 68, 617-625. (SCI, IF=7.5)

Yang, L., Zhao, H., Li, C. P.,* Fan, S., and Li, B. Dual β-cyclodextrin functionalized Au@SiC nanohybrids for the electrochemical determination of tadalafil in the presence of acetonitrile.  Biosens. Bioelectron., 2015, 64, 126-130. (SCI, IF=7.5)

Yang, L., Zhao, H., Fan, S., Deng, S., Lv, Q., Lin, J., and Li, C. P.* Label-free  electrochemical immunosensor based on gold-silicon carbide nanocomposites for sensitive detection of human chorionic gonadotrophin.  Biosens. Bioelectron., 2014, 57, 199-206. (SCI, IF=6.4)

Ye, H., Yang, L., Zhao, G., Zhang, Y., Ran, X., Wu, S., Zou, S., Xie, X.,* Zhao, H.,*  and Li, C. P.* A FRET-based fluorescent approach for labetalol sensing using calix[6]arene functionalized MnO2@graphene as a receptor. RSC Adv., 2016, 6, 79350-79360. (SCI, IF=3.3)

Ran, X., Yang, L., Zhang, J., Deng, G., Li, Y., Xie, X., Zhao, H.,* and Li, C. P.* Highly  sensitive electrochemical sensor based on β-cyclodextrin-gold@3, 4, 9, 10-perylene tetracarboxylic acid functionalized single-walled carbon nanohorns for simultaneous determination of myricetin and rutin.  Anal. Chim. Acta, 2015, 892, 85-94. (SCI, IF=4.7)

Yang, L., Zhao, H., Li, Y., and Li, C. P.* Electrochemical simultaneous determination of hydroquinone and p-nitrophenol based on host-guest molecular recognition capability of dual β-cyclodextrin functionalized Au@graphene nanohybrids.  Sens. Actuators B-Chem, 2015, 207, 1–8. (SCI, IF=4.8)

Yang, L., Zhao, H., Li, Y., Ran, X., Deng, G., Zhang, Y., Ye, H., Zhao, G., and Li, C. P.* Indicator displacement assay for cholesterol electrochemical sensing using calix[6]arene functionalized graphene-modified electrode.  Analyst, 2016, 141, 270-278. (SCI, IF=4.0)  (Back Cover)

Yang, L., Zhao, H., Deng, G., Ran, X., Li, Y. and Li, C. P.* Immunosensor for prostate-specific antigen using Au/Pd@flower-like SnO2 as platform and Au@mesoporous carbon as signal amplification.  RSC Adv., 2015, 5, 74046-74053. (SCI, IF=3.3)

Yang, L., Zhao, H., Fan, S., Zhao, G., Ran, X., and Li, C. P.* Electrochemical detection of cholesterol based on competitive host–guest recognition using a β-cyclodextrin/poly(N-acetylaniline)/ graphene-modified electrode. RSC Adv., 2015, 5, 64146-64155. (SCI, IF=3.3)

Ran, X., Yang, L., Zhao, G., Ye, H., Zhang, Y., Fan, S., Xie, X.,* Zhao, H.,* and Li,

C. P.* Simultaneous determination of two flavonoids based on disulfide linked β-cyclodextrin dimer and Pd cluster functionalized graphene-modified electrode.  RSC Adv., 2015, 5, 60775-60785. (SCI, IF=3.3)

Yang, L., Zhao, H., Fan, S., Li, B. and Li, C. P.* A highly sensitive electrochemical sensor for simultaneous determination of hydroquinone and bisphenol A based on the ultrafine Pd nanoparticle@TiO2 functionalized SiC.  Anal. Chim. Acta, 2014, 852, 28–36.  (SCI, IF=4.5)

Li, C. P.,*He, Z., Wang, X., Yang, L., Yin, C., Zhang, N., Lin, J., and Zhao, H.* Selenization of ovalbumin by dry-heating in the presence of selenite: effect on protein structure and antioxidant activity. Food Chem., 2014, 148, 209-217. (SCI, IF=3.3)

Yin, C., Yang, L., Zhao, H., and Li, C. P.* Improvement of antioxidant activity of egg white protein by phosphorylation and conjugation of epigallocatechin gallate.  Food Res. Int., 2014, 64, 855-863. (SCI, IF=2.8)

Li, C. P.,* Fan, S., Yin, C., Zhang, N., Du, S., and Zhao, H. Carboxylic silica nanosheets-platinum nanoparticles modified glass carbon electrode for pesticides detection.  Anal. Methods, 2014, 6, 1914-1921. (SCI, IF=1.8)

Zhao, J., Zhao, H., Wang, X., Huang, R., Enomoto, H., He, Z., and Li, C. P.*  Characteristics and enhanced antioxidant activity of egg white protein selenized by dry-heating in the presence of selenite.  J. Agric. Food Chem., 2013, 61, 3131-3139. (SCI, IF=2.9)

Huang, R., Li, C. P.*, Chen, D., Zhao, G., Cheng, W., Zhang, Y., and Zhao, H.* Preparation of phosphorylated starch by dry-heating in the presence of pyrophosphate and its calcium-phosphate solubilizing ability.  J. Food Sci. & Technol., 2013, 50, 561-566. (SCI, IF=2.0)

Li, C. P.,* Peng, J. L., Zhu, G. H., and Li, C. Micellar calcium phosphate- cross-linkage in donkey casein micelles. Milchwissenschaft, 2010, 65, 274-276. (SCI)

Li, C. P.,* Peng, J. L., Dong, B. S., Zhao, H., and Ou, L. C. Formation of micelles and micellar calcium phosphate-cross-linkage in artificial buffalo caseinmicelles. Milchwissenschaft, 2010, 65, 432-434. (SCI)

Li, C. P.,* Chen, D., Peng, J., Enomoto, H., Hayashi, Y., Li, C., Ou, L., and Aoki, T. Improvement of functional properties of whey soy protein by phosphorylation by dry-heating in the presence of pyrophosphate.  LWT-Food Sci. & Technol., 2010, 43, 919-925. (SCI, IF=2.2)

Li, C. P.,* Enomoto, H., Hayashi, Y., Zhao, H., and Aoki, T. Recent advances in phosphorylation of food protein: A review.  LWT-Food Sci. & Technol., 2010, 43, 1295-1300. (SCI, IF=2.2)

Li, C. P.,*Peng, J. L., Ke, H. F., Chen, D. Y., Zhu, G. H., Ou, L. C., and Miao, Y. W. Micellar calcium phosphate-cross-linkage in buffalo casein micelles.  Milchwissenschat, 2010, 65, 41-43. (SCI)

Li , C. P.,* Hayashi, Y., Enomoto, H, Hu , F., Sawano, Y., Tanokura, M. and Aoki, T. Phosphorylation of proteins by dry-heating in the presence of pyrophosphate and some characteristics of introduced phosphate groups.  Food Chem., 2009, 114, 1036-1041. (SCI, IF=3.1)

Li, C. P., Akasaki, E., Zhao, Y. and Aoki, T. Micellar calcium phosphate-cross- linkage in yak casein micelles.  Milchwissenschaft, 2006, 61, 288-292. 

Li, C. P., Hayashi, Y., Shinohara, H., Ibrahim, H. R., Sugimoto, Y., Kurawaki, J., Matsudomi, N., and Aoki, T. Phosphorylation of ovalbumin by dry-heating in the presence of pyrophosphate: effect on protein structure and some properties.  J. Agric. Food Chem., 2005, 53, 4962-4967.  (SCI, IF=2.5)

Li, C. P., Enomoto, H., Ohki, S., Ohtomo, H., and Aoki, T. Improvement of functional properties of whey protein isolate through glycation and phosphorylation by dry-heating.  J. Dairy Sci., 2005, 88, 4137-4145. (SCI, IF=2.2)

Li, C. P., Ibrahim H. R., Sugimoto, Y., Hatta, H., and Aoki, T. Improvement of functional properties of egg white protein through phosphorylation by dry-heating in the presence of pyrophosphate.  J. Agric. Food Chem., 2004, 52, 5752-5758. (SCI, IF=2.3)

Li, C. P., Salvador, A. S., Ibrahim H. R., Sugimoto, Y., and Aoki, T. Phosphorylation of egg white proteins by dry-heating in the presence of phosphate.  J. Agric. Food Chem., 2003, 51, 6808-6815. (SCI, IF=2.1)

Deng, G. and Li, C. P.,* Heat-induced aggregation inhibition properties of phosphorylated ovalbumin through its molecular chaperone-like properties. Food Sci., 2017, 38, 66-73. (EI)

Umeda, T.,Li, C. P., and Aoki, T. Formation of micelle and micellar calcium phosphate-cross linkage in artificial porcine casein micelles.  Milchwissenschaft, 2005, 60, 372-375.

Umeda, T., Li, C. P, and Aoki, T. Micellar calcium phosphate-cross-linkage in ovine casein micelles. Milk Sci., 2005,54, 63-68.

Enomoto, H., Li, C. P., Morizane, K., Ibrahim H. R., Sugimoto, Y., Ohki, S., Ohtomo, H. and Aoki, T. Glycation and phosphorylation of b-lactoglobumin by dry-heating：effect on protein structure and some properties.  J. Agric. Food Chem., 2007, 55, 2392-2398. (SCI, IF=2.5)

Enomoto, H.; Li, C. P., Morizane, K., Ibrahim, H.R., Sugimoto, Y., Ohki, S., Ohtomo, H.and Aoki, T. Improvement of functional properties of bovine serum albumin through phosphorylation by dry-heating in the presence of pyrophosphate.  J. Food Sci., 2008, 73, C84-C91. (SCI, IF=1.6)

Hayashi, Y., Li, C. P., Enomoto, H., Ibrahim, H. R., Sugimoto, Y. and Aoki, T. Improvement of functional properties of ovotransferrin by phosphorylation through dry-heating in the presence of pyrophosphate.  Asian-Aust. J. Anim. Sci. 2008,21, 596-602. (SCI)

Enomoto, H., Nagae, S., Hayashi, Y., Li, C. P., Ibrahim, H. R., Sugimoto, Y. Aoki T. Improvement of functional properties of egg white protein through glycation and phosphorylation by dry-heating.  Asian-Aust. J. Anim. Sci., 2009,22, 591-597.

Hayashi, Y., Nagano, S., Enomoto, H., Li, C. P., Sugimoto, Y., Ibrahim, H. R., Hatta, H., Takeda, C. and Aoki T. Improvement of foaming property of egg white protein by phosphorylation through dry-heating in the presence of pyrophosphate.  J. Food Sci., 2009, 74, C68-C72. (SCI, IF=1.6)

Enomoto, H., Hayashi, Y., Li, C. P., Ohki, S., Ohtomo, H., Shiokawa, M.,Aoki, T. Glycation and phosphorylation of alpha-lactalbumin by dry heating: effect on protein structure and physiological functions.  J. Dairy Sci., 2009, 92, 3057-3068. (SCI, IF=2.3)

Enomoto, H., Ishimaru, T., Li, C. P., Hayashi, Y., Matsudomi, N., Aoki, T. Phosphorylation of ovalbumin by dry-heating in the presence of pyrophosphate: Effect of carbohydrate chain on the phosphorylation level and heat stability. Food Chem., 2010, 122, 526-532.  (SCI, IF=3.1)

Liu, Y., Wang, G., Li, C. P., Zhou, Q., Wang, M., Yang, L. A novel acetylcholinesterase biosensor based on carboxylic graphene coated with silver nanoparticles for pesticide detection.  Mate.Sci.Engin.: C, 2014,35, 253-258. (SCI, IF=3.0)

李灿鹏*,陈德义,赵逸云,青木孝良. 食品蛋白质磷酸化改性的研究进展. 食品科学，2009, 30, 252-255.

成伟华，付国平，沙勐，赵改红，李灿鹏*. 生物大分子的硫酸化修饰及其生物活性的研究进展. 天然产物研究与开发, 2012, 10, 1486-1490.

李灿鹏，杨龙，庞芳，杨周，王光灿. 钯-四氧化三铁纳米复合物生物传感器的制备及检测有机磷农药的研究, 分析实验室, 2013, 32, 5-9.

和智坤，赵改红，李梦婷，王晓燕，李灿鹏*. 魔芋葡甘露寡糖的干燥加热硒酸化及其产物的抗氧化性. 食品科学,  2013, 5, 5-9.          

陈明勇，彭剑林，李灿鹏*. 双团棘胸蛙(Paa yunnanensis)肌肉营养成分分析与评价.云南大学学报，2010, 32, 114-117.

李灿鹏, 林葉子,榎元廣文, 八田一, 青木孝良. リン酸塩存在下での乾燥加熱による食品タンパク質のリン酸化．多機能化. New Food Industry 2006, 48, 29-36. (日文)

2、出版教材

[1]  张志胜， 李灿鹏，毛学英 主编. 乳与乳制品工艺学，北京：中国质检出版社，中国标准出版社，2014.

[2]  李灿鹏，吴子健 主编. 蛋品科学与技术，北京：中国质检出版社，中国标准出版社，2013.

[3]  刘红英，高瑞昌，戚向阳 主编. 食品化学，北京：中国质检出版社，中国标准出版社，2013. (李灿鹏 副主编)

3、专利

[1]  李灿鹏、曾祥慧、赵 卉、朱光辉、李聪、欧灵澄。一种硒酸化多糖的制备方法。中国发明专利，已批准，专利号：ZL 2009 1 0094679.2

4、入选人才培养情况

[1]  2010年11月，入选“云南省第十三批中青年学术与技术带头人后备人选”

[2]  2010年12月，入选“昆明市第八批中青年学术与技术带头人后备人选”

[3]  2010年12月，入选“云南大学第三批中青年骨干教师培养计划”

[4]  2016年05月，入选“云南大学第三批青年英才教师培养计划”

5、获奖情况

[1]  2016.11，获得云南大学 第二十届伍达观教育基金优秀教师奖

[2]  2016.06，获得“云南启迪杯”第二届云南省“互联网+”大学生创新创业大赛优秀创新创业导师奖

主持和参加的项目

[1]  国家自然科学基金“基于超分子主体/鳞片状MnO2纳米复合材料的电化学生物传感器的构建及其在新型肿瘤标志物检测中的应用”（21565029），执行时间：2016.1-2019.12。（主持）

[2]  国家自然科学基金“基于硒酸化的蛋清蛋白功能特性改善及其机理研究” （31160334），执行时间：2012.1-2015.12。（主持）

[3]  国家科技支撑计划项目“云南天然橡胶产业关键技术研究与集成示范”子项目“橡胶籽油、复混肥、食用菌的研究与开发及低蛋白浓缩天然胶乳生产关键技术集成与产业化开发”(2011BAD30B00)，执行时间：2011-2014年。（主持）

[4]  云南省自然科学基金“基于硒酸化的乳源肽抗氧化性的增强及其机理研究（2012FB112）,执行时间：2012-2015年。（主持）

[5]  云南省自然科学基金 “螺旋藻蛋白和多糖的磷酸化及多功能化研究”. (2007C155M),

执行时间：2007-2010年。（主持）

[6]  云南省教育厅基础科学研究基金重大专项项目“魔芋葡甘聚糖的硒酸化及其抗癌、抗氧化研究”. (ZD2009002)，执行时间：2010-2011年。（主持）

[7]  中华全国供销总社合作社昆明食用菌研究所委托研究项目“低氟砖茶的研制(横向)”，执行时间：2009-2011年。（主持）

[8]  云南省热带作物研究所委托研究项目“辣木叶中辣木碱（Moringine）的定量方法研究”(横向)，2011年（主持）

[9]  河口橡胶股份有限公司合作研究项目 “低蛋白浓缩胶乳的中试生产线建设”。 执行时间: 2013-2014年。（主持）

[10]  云南省社会发展科技计划项目“新型金属-碳纳米生物传感器的制备及其在有机磷和氨基甲酸酯类农残检测中的应用”（2014RA022）. 执行时间：2014.6-2017.6年。（参加）

参加的学术会议

 第九届食品科学国际年会 辽宁 沈阳 2016.7（参会）

 International Symposium on Analytical Biosensors – Changsha, Hunan, Nov 3, 2015  

(Poster)

 第十八届大环化学暨第十届超分子化学学术讨论会, 湖南 长沙, 2016.8. (分会场报告)

社会兼职

[1]  《Science Today》  编委

[2]  《食品研究与开发》 编委

[3]  云南省预防医学会第二届食品安全分会 委员

[4]  云南省奶业协会 常务理事

[5]  云南省食品安全标准专家委员会 专家