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食品研究与开发:2024,45(7):103-108
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金丝小枣全枣、枣皮、枣肉黄酮提取物的抗氧化活性和免疫活性
(河北农业大学 食品科技学院,河北 保定 071000)
Antioxidant and Immune Activity of Total Flavonoids Extracts from the Whole,Skin and Flesh of Ziziphus jujuba
(College of Food Science and Technology,Hebei Agricultural University,Baoding 071000,Hebei,China)
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投稿时间:2023-02-12    
中文摘要: 以金丝小枣为研究对象,分别测定金丝小枣全枣、枣皮、枣肉的黄酮提取物对DPPH·、ABTS+·、·OH 清除能力和总还原力,并利用刀豆蛋白A(concanavalin A,ConA)和脂多糖(lipopolysaccharide,LPS)分别诱导小鼠脾脏T 淋巴细胞和B 淋巴细胞增殖反应,探究金丝小枣的全枣、枣皮、枣肉的黄酮提取物的免疫活性。试验结果表明:金丝小枣全枣、枣皮、枣肉黄酮抗氧化活性和免疫活性存在差异,枣皮黄酮的抗氧化活性和免疫活性最强,枣肉黄酮提取物的抗氧化活性和免疫活性最弱,但全枣、枣皮、枣肉黄酮提取物对DPPH·和·OH 的清除活性高于VC,且全枣、枣皮、枣肉黄酮提取物对小鼠脾脏T 淋巴细胞、B 淋巴细胞的增殖均具有促进作用。
中文关键词: 金丝小枣  黄酮  提取  抗氧化活性  免疫活性
Abstract:In this study,the scavenging capacity and total reducing capacity of the total flavonoid extracts of the whole,skin and flesh of Ziziphus jujuba on DPPH·,ABTS+·,·OH were measured.Additionally,mouse splenic T lymphocytes and B lymphocytes were induced separately using concanavalin A(ConA)and lipopolysaccharide(LPS)to investigate the immunomodulatory activities of the flavonoid extracts.The results indicated variations in the antioxidant and immune activities among the total flavonoids from the whole date,the skin and the flesh of Ziziphus jujuba.The total flavonoids from the skin of the jujube had the strongest antioxidant and immune activities,while the total flavonoids from the flesh of the jujube had the weakest antioxidant and immune activities.However,all three jujube parts showed higher scavenging activities against DPPH·and·OH radicals compared to vitamin C.The total flavone extracts from whole jujube,jujube skin and jujube flesh could promote the proliferation of mouse splenic T lymphocytes and B lymphocytes.
文章编号:202407015     中图分类号:    文献标志码:
基金项目:河北农业大学引进人才科研专项(YJ2020024);“十四五”国家重点研发计划项目(2022YFD1600400)
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