Abstract:Collagen is the most abundant and widely distributed protein in multicellular organisms，and it is one of the proteins that maintains human health.Due to its unique properties，collagen has been widely used in many fields such as food，cosmetics and medicine.Fish skin，a by-product in fish processing，is rich in proteins which are dominated by collagen.Therefore，fish skin has a high economic value and processing potential.The present paper comprehensively analyzed the extraction methods，molecular characteristics，research status and application of collagen from fish skin，which was of theoretical guiding significance for comprehensive processing and product development of fish.