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食品研究与开发:2021,42(19):219-224
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非淀粉多糖对肠道菌群的调节作用及其对代谢疾病影响的研究概述
(青海大学农牧学院,青海 西宁 810016)
Regulatory Effects of Non-Starch Polysaccharides and Intestinal Microbiota and Their Effects on Metabolic Diseases
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投稿时间:2021-05-27    
中文摘要: 膳食纤维中的非淀粉多糖(non-starch polysaccharides,NSPs)是由若干个单糖通过糖苷键连接而成的多聚体,包括纤维素、半纤维素、果胶、树胶、β-葡聚糖、果聚糖以及半乳糖等低聚糖。NSPs无法被机体消化或难以消化,因此它们几乎能完整地通过肠道,并被肠道内的微生物菌群发酵选择性地刺激肠道内微生物的增殖和活性,从而改善肠道菌群的环境。肠道微生物菌群在代谢综合征的发病机制中发挥着重要作用,通过使用益生元或益生菌来控制肠道微生物菌群,可以减少肠道低度炎症,改善肠道屏障的完整性,从而改善代谢平衡,促进减肥。因此NSPs改善肠道菌群的同时,也调节代谢疾病。该文总结NSPs与肠道菌群相互作用及改善代谢疾病的研究进展,为今后NSPs的利用提供参考。
Abstract:Non-starch polysaccharides (NSPs)in dietary fiber are polymers composed of several monosaccharides linked by glycosidic bonds.NSPs include cellulose,hemicellulose,pectin,gum,β-glucan,fructan,galactose,and other oligosaccharides.NSPs cannot be digested by the body or are difficult to digest,so they can pass through the intestine almost unaltered.Fermentation of NSPs by intestinal tract microbial flora selectively stimulates the proliferation and activity of intestinal tract microorganisms,which can improve the environment of the intestinal flora.The intestinal microbiota plays an important role in the pathogenesis of metabolic syndrome.The use of prebiotics or probiotics to control the intestinal microbiota can reduce low-grade intestinal inflammation,improve the integrity of the intestinal barrier,and thereby improve metabolism balance and promote weight loss.Therefore,NSPs can improve the intestinal flora while regulating metabolic diseases.This review article summarizes the research progress concerning the interaction of NSPs with intestinal flora and the influence of the improvement of metabolic diseases.The review provides a reference for the utilization of NSPs.
文章编号:202119031     中图分类号:    文献标志码:
基金项目:青海省科技计划项目(2018-ZJ-728)
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