Abstract:Cherry tomato preserves are agricultural products for export in China，and the residues of chlormequat chloride have become a bottleneck restricting its export，therefore，a detection method of the residues was established.The processed products of cherry tomato preserves were selected as the research object，the chlormequat chloride was extracted through the methanol，then the extraction was separated and purificated by strong cation solid-phase extraction （SPE）and detected by HPLC/MS/MS，the reliability of detection method was analyzed at the same time.The results showed that the detection and quantification limit of the method was 0.01 mg/kg and 0.02 mg/kg respectively，the recovery was 73.33%-90.60%and the precision was 3.34%-7.87%.The method provided a basis for the investigation of the content of chlormequat chloride in tomato and the degradation of chlormequat chloride residues.