Abstract:Collagen with excellent biocompatibility， biodegradability， and weak antigenicity， has been used in food， medicine， cosmetics， and other fields. However， the application of terrestrial collagen is limited due to the emergence of problems such as religious beliefs， allergic reactions， and disease transmission. Jellyfish resources are abundant in coastal areas of China， and the total collagen dry matter content of edible jellyfish ranges from 122.64 to 693.92 mg/g， accounting for about half of its total protein content， which can be used as a good source of marine collagen. The extraction methods and mechanisms of jellyfish collagen were systematically reviewed， as well as the biological activities of jellyfish collagen and its hydrolysate. Additionally， the application and research progress of jellyfish collagen in the fields of food， pharmaceutical materials， and cosmetics were summarized， and the extraction and utilization of jellyfish collagen were prospected， aiming to provide more ideas for the further development and utilization of jellyfish collagen.