Abstract:Taking Cinnamomum migao H.W.Li as the experimental material，the response surface method was used to optimize the extraction process of polysaccharides，and the antioxidant activity of polysaccharides was studied.Establish a quantitative analysis method for the determination of polysaccharide content by ultraviolet spectrophotometry with glucose as the reference substance.On the basis of single factor experiment，taking ultrasonic time，extraction power and liquid-to-material ratio as independent variables，and polysaccharide yield rate as dependent variable.Box-Behnken design was used to optimize the extraction process of polysaccharides from sesame seeds.The anti-oxidant activity of polysaccharides was studied by scavenging DPPH free radicals，superoxide anion free radicals and hydroxyl free radicals.The results showed that the optimal extraction process conditions for polysaccharides were ultrasonic time 35 min，extraction power 80 W，liquid to material ratio 40∶1（mL/g），under these conditions，the polysaccharide yield was 5.92%.The polysaccharides had strong scavenging ability against DPPH free radicals，superoxide anion free radicals and hydroxyl free radicals.Within a certain concentration range，the higher the polysaccharide concentration，the stronger the antioxidant activity.