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投稿时间：2019-12-24
投稿时间：2019-12-24
中文摘要: 该试验分别采用FeSO4/VC和偶氮二异庚腈[2，2'-azobis（2，4-di-methylvaleronitrile），AMVN]诱导鱼肝油氧化，研究迷迭香提取物对鱼肝油脂质氧化的抑制作用，同时测定迷迭香提取物在胃肠道消化过程中对鱼肝油氧化的抑制作用。结果表明：迷迭香提取物（终浓度为10 μg/mL～500 μg/mL）能够显著抑制FeSO4/VC和AMVN诱导的鱼肝油氧化（p＜0.05）；与FeSO4/VC和AMVN诱导鱼肝油氧化模型组相比，添加终浓度为500 μg/mL的迷迭香提取物（rosemary extract，RE）可使丙二醛（malondialdehyde，MDA）含量分别下降93.47%和60.16%。此外，经过模拟胃肠道消化后，迷迭香提取物同样能够抑制鱼肝油氧化，且抑制效果随其浓度的升高而增强。
Abstract:The aim of this work was to investigate the inhibitory effects of rosemary extract（RE）on oxidation of cod liver oil induced by FeSO4/VCas well as 2，2'-azobis（2，4-di-methylvaleronitrile）（AMVN）.Meanwhile，the inhibition effect of RE on oxidation of cod liver oil during the simulated digestion were also measured.The results showed that RE（at final concentration of 10 μg/mL to 500 μg/mL）could significantly inhibite oxidation of cod liver oil induced by FeSO4/VCor AMVN.As compared with the samples treated by FeSO4/VCor AMVN，the RE at a final concentration of 500 μg/mL could inhibite the formation of malondialdehyde（MDA）by 93.47% and 60.16%，respectively.In addition，RE was also shown strong inhibition effect on oxidation of cod liver oil during the simulated gastrointestinal digestion in a dose depend manner.
keywords: rosemary extract lipid oxidation simulated gastric and intestinal digestion inhibition capacity
文章编号：202021005 中图分类号： 文献标志码：
基金项目:国家自然科学基金（31501491）
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