Abstract:Ultra-performance liquid chromatography-tandem mass spectrometry（UPLC-MS/MS）was used to analyze the interference of dye precipitation in stationery and packing materials on aquatic products gentian violet detection.Samples like black pen marking paper，black mark pen marking paper，blue ballpoint pen marking paper，labell paper，thermal labels and sample plastic bag were extracted with acetonitrile and analyzed by UPLC-MS/MS.The results showed that the residue of gentian violet was detected in all the samples except for the black marking paper.The contents of gentian violet and leuco gentian violet were increased in different degrees along with the extension of time.The gentian violet was higher in blue ballpoint pen marking paper，label paper and thermal labels.Gentian violet was detected in black marker pen marking paper and sample plastic bag.