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食品研究与开发:2020,41(13):43-49
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雪莲培养物保健食品的抗氧化功能研究
(北京同仁堂健康药业股份有限公司研发中心,北京100085)
Study on Antioxidant Function of the Health-Care Food of Tissue Culture of Saussurea involucrata
(The R&D Center of Beijing TongRenTang Health-Pharmaceutical Co.,Ltd.,Beijing 100085,China)
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投稿时间:2020-01-06    
中文摘要: 对雪莲培养物与海洋鱼胶原蛋白、针叶樱桃果粉和透明质酸钠组成的保健食品的抗氧化功能进行研究。动物实验证明,该保健食品能降低大鼠血清和肝组织中过氧化脂质(lipid peroxide,LPO)含量,提高超氧化物歧化酶(superoxide dismutase,SOD)的活性,提高血清和脑组织中的谷胱甘肽(glutathione,GSH)的含量。人体试食试验证明,试食组人群连续服用雪莲培养物抗氧化保健食品3个月后,血液过氧化脂质(malondialdehyde,MDA)含量平均下降13.93%,血液超氧化物歧化酶活性平均升高10.39%,血液谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-Px)活性平均升高9.92%。试食组的以上3项指标均极显著高于对照组(P<0.01),且试食组自身前后比较及试食后与对照组的组间比较差异均有极显著性(P<0.01)。据此判定,该保健食品具有抗氧化功能。
Abstract:The anti-oxidation function of the health-care food of tissue culture of Saussurea involucrata,marine fish collagen,acerola cherry powder and sodium hyaluronate was studied.Animal experiments have shown that the health-care food can reduce the content of lipid peroxide (LPO)in serum and liver tissue of rats,increase the activity of superoxide dismutase(SOD),and increase the content of glutathione(GSH)in serum and brain tissue.The human body test showed that,for people in the test group after 3 months of continuous administration of the health-care food,the content of malondialdehyde (MDA)in blood was decreased by 13.93%on average,the activity of superoxide dismutase (SOD)and the glutathione peroxidase (GSH-Px)in blood were increased by 10.39%and 9.92%on average,respectively.The above three indexes of the test group were significantly higher than those of the control group (P<0.01),and the comparison of the test group before and after itself and the comparison between the test group and the control group were extremely significant(P<0.01).The above results show that the health-care food of tissue culture of saussureainvolucrata has anti-oxidation function.
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