Abstract:Sea cucumber glycosides was main active substance of sea cucumber，which had great development value and potential application. But the content of the sea cucumber glycosides in sea cucumber was low and structure was complicated， difficult to fully extract and analyse. So the sea cucumber glycosides extraction and analysis has become a hot research topic. In this paper，the research progress of Sea cucumber glycosides was discussed from its extraction，purification and analytical method. It provided good clues and evidence for further study on sea cucumber glycosides.