Abstract:As a new type of food processing method，cold plasma has broad application prospects in improving product safety and extending food shelf life.The mechanism of action of the cold plasma determines that it can rapidly kill microorganisms at low temperatures，degrade various mycotoxins and leave no known chemical residues.Therefore，this paper focused on the mechanism and mode of action of low temperature cold plasma，the killing and degradation effects and mechanisms of microbes and mycotoxins，and it was used in multiple industries such as fresh agricultural products，liquid foods，cereals and meat.Research progress in sterilization and degradation of mycotoxins provided a new view and idea for the control of bacteria and mycotoxins in food samples.