本文已被:浏览 3730次 下载 0次
投稿时间:2018-09-11
投稿时间:2018-09-11
中文摘要: 为优化党参山楂健脾养胃咀嚼片的配方工艺,采用单因素试验对矫味剂、黏合剂、润滑剂和片剂硬度进行筛选;采用混料设计试验研究配方中5 种成分的不同配比组合对咀嚼片感官质量的影响,优选出最佳配方。确定的最佳配方为:干膏粉95.60%、阿斯帕坦1.80%、柠檬酸0.80%、薄荷香精0.80%、桔子香精0.50%,以体积分数为95%乙醇为黏合剂,质量分数为0.50%的硬脂酸镁为润滑剂,压片硬度50 N。按此配方制得的党参山楂健脾养胃咀嚼片表面光滑圆整、色泽均匀、酸甜适中、口感良好。
Abstract:In order to optimize the formulation process of Dangshen Shanzha nourishing the stomach and spleen chewable tablets,the hardness of flavoring agent,adhesive,lubricant and tablet was screened by single factor test;the five components of the formula were studied by mixing design experiment.The optimal formulation was preferred for the effect of different combinations of combinations on the sensory quality of the chewable tablet.The best formula determined was dry paste powder 95.60%,aspartame 1.80%,citric acid 0.80%,mint flavor 0.80%,orange flavor 0.50%,with 95%by volume of ethanol as binder,mass fraction was 0.50%magnesium stearate was a lubricant and the tableting hardness was 50N.The formula of Dangshen Shanzha nourishing the stomach and spleen chewable tablets prepared according to this formula had a smooth and round surface,uniform color,moderate sweet and sour taste and good taste.
keywords: mixed design Codonopsis pilosula hawthorn spleen and stomach chewable tablets formula optimization
文章编号:201918015 中图分类号: 文献标志码:
基金项目:国家重点研发计划项目(2018YFC1706300);甘肃省创新引导专项资金项目(2017ZX-02);甘肃省科技厅科技重大专项项目(17ZD2FA009);国家中药标准化项目(ZYBZH-Y-GS-10);兰州市科技计划项目(2016-2-80、2017-4-119、2017-RC-115);中央高校基本业务费重点项目和自由探索项目(lzujbky-2018-k13)
Author Name | Affiliation |
YE Mei-yu,WANG Yan-ping,ZHANG Jing,MA Ming,LIU Jing-long,HU Fang-di | College of Pharmacy,Lanzhou University,Lanzhou 730000,Gansu,China |
引用文本: