Abstract:As an effective conserver of plant genetic resources，seed plays an important role in the continuation of species，and is also an important source of germplasm innovation. Because of its bacteriostasis，it has been widely studied and applied in medical and edible fields. In this paper，the inhibitory effects of antimicrobial proteins，polyphenols，proanthocyanidins，alkaloids and other active substances in the seeds of Ginkgo biloba，Sophora flavescens，job's tears and radish on bacteria or fungi such as Escherichia coli，Staphylococcus aureus，Aspergillus niger，Penicillium，Mucor were discussed，and their antiseptic applications in fruits，vegetables，meat and other foods were summarized. In order to provide a reference for the study of seed bacteriostasis.