Abstract:The extracts of Platycodon grandiflorum root were extracted with different solvents，and the content and antioxidant activity of total polyphenols and total flavonoids in different solvent extracts were compared and analyzed.Petroleum ether，n-butanol，ethyl acetate and n-hexane were used to perform liquid-liquid extraction on the aqueous solution of Platycodon grandiflorum root extract to obtain different solvent extracts of the sample.The content of total polyphenols and total flavonoids in different solvent extracts and their antioxidant activity were determined.The extract of Platycodon grandiflorum root extract had the highest total polyphenol content and the petroleum ether extract had the highest total flavonoid content.Each solvent extract exhibited different degrees of antioxidant activity and showed a dose-dependent order in the order：n-butanol，petroleum ether，ethyl acetate and n-hexane.The extracts of n-butanol and petroleum ether could be used for the separation and purification of total polyphenols and total flavonoids.Considering the antioxidant activity，n-butanol extract could be used as a natural antioxidant in food and pharmaceutical fields.