Abstract:As a valuable Chinese herbal medicine，American ginseng has a wide variety of chemical components and a wide range of biological activities.It is favored by people all over the world.Ginsenoside is the main active ingredient in American ginseng.The biotransformation of American ginseng and ginseng saponins by different fungi （food medicinal fungi，filamentous fungi，American ginseng endophytic fungi），the types of transformation products，the composition changes and their effects were reviewed，it provided a certain reference value for the efficient development and utilization of American ginseng.